Cold storage is the safest way to store cryptocurrency, and a Ledger or other cold storage device is the most secure way to do it. Cold storage devices are designed to keep your coins safe from hackers and other threats. They also allow you to store your coins offline, meaning they are not connected to the internet, which reduces the risk of theft or hacking. Having a hot wallet is also a good idea, as it allows you to quickly access your funds if needed, but it is important to remember that hot wallets are not as secure as cold storage devices and should only be used for small amounts of money. It is recommended that 80-90% of your cryptocurrency be stored in cold storage, with the remaining 10-20% stored in a hot wallet. With this setup, you can easily access your funds when needed, while keeping the majority of your funds safe and secure.